LUZP4

Across TCGA cell cohorts, LUZP4 mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible LUZP4-associated genes across cancer lineages are EQTN, CFC1B, and TMEM252. Each is linked with LUZP4 in more than 1 cancer types. Because this analysis shows association rather than direction, both LUZP4-to-partner and partner-to-LUZP4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, EQTN grouped by LUZP4-low versus LUZP4-high in BREAST.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LUZP4→partner) and Y-score (partner→LUZP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	EQTN →	+0.133	+3.662	<.001	.009	3	1
BREAST	CFC1B →	+0.004	+4.196	<.001	.006	3	1
BREAST	TMEM252 →	+0.304	+3.758	<.001	.007	3	1
BREAST	TMEM207 →	+0.129	+3.672	<.001	.006	3	1
BREAST	CLEC6A →	+0.014	+3.672	<.001	.006	3	1
LARGE_INTESTINE	PPP1R2C →	+0.052	+4.510	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

EQTN by LUZP4 expression — BREAST

Explore this box plot interactively →