LUZP1

Across TCGA cell cohorts, LUZP1 mutation is significantly associated with the RNA expression of many other genes, with 207 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible LUZP1-associated genes across cancer lineages are ZNF479, LIM2, and LCE2A. Each is linked with LUZP1 in more than 2 cancer types. Because this analysis shows association rather than direction, both LUZP1-to-partner and partner-to-LUZP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ZNF479 grouped by LUZP1-low versus LUZP1-high in PANCREAS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LUZP1→partner) and Y-score (partner→LUZP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	ZNF479 →	+0.019	+5.139	<.001	<.001	3	3
PANCREAS	LIM2 →	+0.037	+4.614	<.001	.004	3	1
PANCREAS	LCE2A →	+0.025	+4.614	<.001	.004	3	1
PANCREAS	SLC22A12 →	+0.005	+4.614	<.001	.004	3	1
PANCREAS	OR2J1 →	+0.005	+4.614	<.001	.004	3	1
PANCREAS	XKR4 →	+0.052	+5.584	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 207 associations by consensus.

ZNF479 by LUZP1 expression — PANCREAS

Explore this box plot interactively →