LURAP1L

Across TCGA patient cohorts, LURAP1L mutation is significantly associated with the total protein of many other genes, with 14 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LURAP1L-associated genes across cancer lineages are JNK2, p62 Lck ligand, and p70-S6K. Each is linked with LURAP1L in more than 1 cancer types. Because this analysis shows association rather than direction, both LURAP1L-to-partner and partner-to-LURAP1L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, JNK2 grouped by LURAP1L-low versus LURAP1L-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LURAP1L→partner) and Y-score (partner→LURAP1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	JNK2 →	+0.199	+2.459	.038	.020	3	1
UCEC	p62 Lck ligand →	+0.364	+2.459	.020	.020	3	1
UCEC	p70-S6K →	+0.203	+2.827	.028	.035	3	1
UCEC	STAT3_pY705 →	-0.540	-3.584	<.001	.002	3	1
UCEC	ATM →	-0.595	-2.459	.006	.020	3	1
UCEC	Cyclin-B1 →	+0.594	+2.459	.028	.020	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

JNK2 by LURAP1L expression — UCEC

Explore this box plot interactively →