LUC7L3

Across TCGA patient cohorts, LUC7L3 protein abundance is significantly associated with the RNA expression of many other genes, with 18,328 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible LUC7L3-associated genes across cancer lineages are C3AR1, DSE, and IL1R1. Each is linked with LUC7L3 in more than 7 cancer types. Because this analysis shows association rather than direction, both LUC7L3-to-partner and partner-to-LUC7L3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LUC7L3 versus C3AR1 in OV, with a Pearson correlation of -0.30.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LUC7L3→partner) and Y-score (partner→LUC7L3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	C3AR1 →	-0.789	-0.179	.004	.003	3	8
OV	DSE →	-0.937	-0.238	<.001	<.001	3	7
GBM	IL1R1 →	-1.361	-0.320	<.001	<.001	3	7
OV	CARD6 →	-0.894	-0.153	.001	.007	3	7
HNSC	JPH2 →	-0.821	-0.176	<.001	<.001	3	7
OV	FLI1 →	-0.647	-0.196	.003	.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,328 associations by consensus.

LUC7L3 vs C3AR1 — OV

Explore this scatter interactively →