LUC7L3

Across TCGA patient cohorts, LUC7L3 mutation is significantly associated with the RNA expression of many other genes, with 877 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LUC7L3-associated genes across cancer lineages are LINC02559, BNIP3P41, and MIR1299. Each is linked with LUC7L3 in more than 1 cancer types. Because this analysis shows association rather than direction, both LUC7L3-to-partner and partner-to-LUC7L3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC02559 grouped by LUC7L3-low versus LUC7L3-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LUC7L3→partner) and Y-score (partner→LUC7L3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	LINC02559 →	+0.814	+4.757	<.001	.004	3	2
HNSC	BNIP3P41 →	+0.039	+7.954	<.001	.008	3	2
LIHC	MIR1299 →	+0.427	+6.149	<.001	.002	3	1
UCEC	LINC02427 →	-0.238	-2.205	.005	.002	3	1
UCEC	LINC01607 →	-0.652	-3.890	<.001	<.001	3	1
UCEC	DCP1A →	+0.444	+1.847	.007	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 877 associations by consensus.

LINC02559 by LUC7L3 expression — CESC

Explore this box plot interactively →