LUC7L3

Across TCGA cell cohorts, LUC7L3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,496 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible LUC7L3-associated GO terms across cancer lineages are Spliceosomal complex assembly, Co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway, and mRNA splice site recognition. Each is linked with LUC7L3 in more than 18 cancer types. Because this analysis shows association rather than direction, both LUC7L3-to-partner and partner-to-LUC7L3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Spliceosomal complex assembly grouped by LUC7L3-low versus LUC7L3-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LUC7L3→partner) and Y-score (partner→LUC7L3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Spliceosomal complex assembly →	+0.103	+1.046	<.001	<.001	3	19
BONE	Co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway →	+0.183	+1.339	<.001	<.001	3	18
UPPER_AERODIGESTIVE_TRACT	mRNA splice site recognition →	+0.125	+0.958	<.001	<.001	3	17
BONE	Co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway →	+0.169	+0.995	<.001	.004	3	16
BONE	Protein localization to cytoplasmic stress granule →	+0.145	+0.954	<.001	.003	3	16
SOFT_TISSUE	Positive regulation of DNA-directed DNA polymerase activity →	+0.203	+1.110	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,496 associations by consensus.

Spliceosomal complex assembly by LUC7L3 expression — LUNG_SCLC

Explore this box plot interactively →