LUC7L

Across TCGA patient cohorts, LUC7L protein abundance is significantly associated with the RNA expression of many other genes, with 9,959 significant associations in total. GBM shows the largest number of these associations.

The most reproducible LUC7L-associated genes across cancer lineages are AXIN1, SNRNP25, and TEDC2. Each is linked with LUC7L in more than 3 cancer types. Because this analysis shows association rather than direction, both LUC7L-to-partner and partner-to-LUC7L results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LUC7L versus AXIN1 in BRCA, with a Pearson correlation of 0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LUC7L→partner) and Y-score (partner→LUC7L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	AXIN1 →	+0.588	+0.351	.001	<.001	3	4
BRCA	SNRNP25 →	+0.622	+0.313	<.001	<.001	3	4
GBM	TEDC2 →	+0.749	+0.516	<.001	<.001	3	4
BRCA	NTHL1 →	+0.794	+0.277	<.001	<.001	3	4
UCEC	P3H4 →	+0.885	+0.244	.002	.009	3	4
BRCA	POLR3K →	+0.708	+0.302	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,959 associations by consensus.

LUC7L vs AXIN1 — BRCA

Explore this scatter interactively →