LUC7L

Across TCGA cell cohorts, LUC7L RNA expression is significantly associated with the go_rna of many other GO terms, with 5,004 significant associations in total. BONE shows the largest number of these associations.

The most reproducible LUC7L-associated GO terms across cancer lineages are DNA double-strand break processing involved in repair via single-strand annealing, Double-strand break repair via single-strand annealing, and Negative regulation of centrosome duplication. Each is linked with LUC7L in more than 13 cancer types. Because this analysis shows association rather than direction, both LUC7L-to-partner and partner-to-LUC7L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA double-strand break processing involved in repair via single-strand annealing grouped by LUC7L-low versus LUC7L-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LUC7L→partner) and Y-score (partner→LUC7L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	DNA double-strand break processing involved in repair via single-strand annealing →	+0.097	+0.944	<.001	<.001	3	14
SOFT_TISSUE	Double-strand break repair via single-strand annealing →	+0.097	+0.944	<.001	<.001	3	14
LUNG_SCLC	Negative regulation of centrosome duplication →	+0.157	+0.770	<.001	<.001	3	13
LUNG_SCLC	Negative regulation of centrosome cycle →	+0.157	+0.770	<.001	<.001	3	13
BONE	DNA topological change →	+0.181	+1.075	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	mRNA splice site recognition →	+0.164	+0.979	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,004 associations by consensus.

DNA double-strand break processing involved in repair via single-strand annealing by LUC7L expression — SOFT_TISSUE

Explore this box plot interactively →