LTV1

Across TCGA cell cohorts, LTV1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,178 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible LTV1-associated GO terms across cancer lineages are Ribosomal small subunit export from nucleus, Ribosomal small subunit biogenesis, and Ribosome biogenesis. Each is linked with LTV1 in more than 19 cancer types. Because this analysis shows association rather than direction, both LTV1-to-partner and partner-to-LTV1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Ribosomal small subunit export from nucleus grouped by LTV1-low versus LTV1-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LTV1→partner) and Y-score (partner→LTV1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Ribosomal small subunit export from nucleus →	+0.140	+1.001	<.001	<.001	3	20
LUNG_SCLC	Ribosomal small subunit biogenesis →	+0.103	+0.769	<.001	<.001	3	20
SKIN	Ribosome biogenesis →	+0.102	+0.909	<.001	<.001	3	19
LIVER	DNA replication initiation →	+0.157	+0.938	<.001	.008	3	19
BONE	Maturation of SSU-rRNA →	+0.110	+0.573	.002	.003	3	19
BLOOD_Lymphoma	Nucleolar large rRNA transcription by RNA polymerase I →	+0.129	+1.200	<.001	<.001	3	18

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,178 associations by consensus.

Ribosomal small subunit export from nucleus by LTV1 expression — LUNG_NSCLC_LUSC

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