LTO1

Across TCGA patient cohorts, LTO1 RNA expression is significantly associated with the RNA expression of many other genes, with 20,638 significant associations in total. ACC shows the largest number of these associations.

The most reproducible LTO1-associated genes across cancer lineages are RAD9A, KDM2A, and METTL3. Each is linked with LTO1 in more than 33 cancer types. Because this analysis shows association rather than direction, both LTO1-to-partner and partner-to-LTO1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LTO1 versus RAD9A in UCS, with a Pearson correlation of 0.53.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LTO1→partner) and Y-score (partner→LTO1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCS	RAD9A →	+0.978	+0.570	<.001	.001	3	34
SCLC	KDM2A →	+1.967	+0.913	<.001	<.001	3	34
CHOL	METTL3 →	+0.981	+0.943	<.001	<.001	3	34
KIRC	TUBGCP6 →	+1.163	+0.790	<.001	<.001	3	34
SCLC	DBF4B →	+1.577	+0.663	<.001	<.001	3	33
UVM	TTC14 →	+1.774	+0.875	<.001	<.001	3	33

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,638 associations by consensus.

LTO1 vs RAD9A — UCS

Explore this scatter interactively →