Across TCGA patient cohorts, LTC4S protein abundance is significantly associated with the RNA expression of many other genes, with 7,382 significant associations in total. GBM shows the largest number of these associations.

The most reproducible LTC4S-associated genes across cancer lineages are PPP1R16B, WAS, and FLI1. Each is linked with LTC4S in more than 4 cancer types. Because this analysis shows association rather than direction, both LTC4S-to-partner and partner-to-LTC4S results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LTC4S→partner) and Y-score (partner→LTC4S) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PPP1R16B →	+1.541	+0.639	.004	.007	3	5
UCEC	WAS →	+1.368	+0.689	<.001	.004	3	5
UCEC	FLI1 →	+1.425	+0.933	.002	.001	3	5
UCEC	POU2AF1 →	+2.638	+0.937	<.001	.001	3	4
HNSC	CSF2RA →	+1.182	+0.844	.003	.001	3	4
UCEC	POU2F2 →	+1.225	+0.652	.003	.008	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,382 associations by consensus.

Exploration

LTC4S survival (RNA) · tumor vs normal (RNA) · all LTC4S data types