Across TCGA patient cohorts, LTC4S mutation is significantly associated with the RNA expression of many other genes, with 16 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LTC4S-associated genes across cancer lineages are RNU6-439P, NPM1P10, and A2ML1-AS2. Each is linked with LTC4S in more than 1 cancer types. Because this analysis shows association rather than direction, both LTC4S-to-partner and partner-to-LTC4S results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LTC4S→partner) and Y-score (partner→LTC4S) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RNU6-439P →	+0.673	+6.392	<.001	.001	3	1
COAD	NPM1P10 →	+0.250	+5.435	<.001	.005	3	1
COAD	A2ML1-AS2 →	+0.234	+5.283	.002	.006	3	1
COAD	RN7SL607P →	+0.578	+5.212	<.001	.007	3	1
UCEC	RN7SKP204 →	+0.576	+4.982	.001	.009	3	1
UCEC	RNU6-1292P →	+1.045	+6.453	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 16 associations by consensus.

Exploration

LTC4S survival (RNA) · tumor vs normal (RNA) · all LTC4S data types