LTBR

Across TCGA patient cohorts, LTBR RNA expression is significantly associated with the protein abundance of many other proteins, with 16,316 significant associations in total. GBM shows the largest number of these associations.

The most reproducible LTBR-associated proteins across cancer lineages are MLF2, FKBP4, and NOP2. Each is linked with LTBR in more than 4 cancer types. Because this analysis shows association rather than direction, both LTBR-to-partner and partner-to-LTBR results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LTBR versus MLF2 in LSCC, with a Pearson correlation of 0.29.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LTBR→partner) and Y-score (partner→LTBR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	MLF2 →	+0.475	+0.515	<.001	.001	3	5
PDAC	FKBP4 →	+0.374	+0.485	<.001	<.001	3	5
LUAD	NOP2 →	+0.451	+0.489	<.001	<.001	3	5
LUAD	PHB →	+0.264	+0.495	.001	<.001	3	5
LUAD	PHB2 →	+0.300	+0.461	<.001	<.001	3	5
GBM	PLEKHA5 →	+0.616	+0.888	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,316 associations by consensus.

LTBR vs MLF2 — LSCC

Explore this scatter interactively →