LTBR

Across TCGA cell cohorts, LTBR RNA expression is significantly associated with the go_rna of many other GO terms, with 5,334 significant associations in total. BONE shows the largest number of these associations.

The most reproducible LTBR-associated GO terms across cancer lineages are Dendritic cell homeostasis, Regulation of cardiac muscle cell membrane potential, and Protein targeting to ER. Each is linked with LTBR in more than 10 cancer types. Because this analysis shows association rather than direction, both LTBR-to-partner and partner-to-LTBR results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Dendritic cell homeostasis grouped by LTBR-low versus LTBR-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LTBR→partner) and Y-score (partner→LTBR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Dendritic cell homeostasis →	+2.411	+4.990	<.001	<.001	3	11
BONE	Regulation of cardiac muscle cell membrane potential →	+0.159	+2.970	<.001	.001	3	10
SOFT_TISSUE	Protein targeting to ER →	+0.104	+2.979	<.001	<.001	3	9
BONE	Response to steroid hormone →	+0.083	+3.881	<.001	<.001	3	9
SOFT_TISSUE	Intracellular sodium ion homeostasis →	+0.195	+3.415	<.001	<.001	3	9
BONE	Protein localization to endoplasmic reticulum →	+0.118	+3.030	.002	.003	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,334 associations by consensus.

Dendritic cell homeostasis by LTBR expression — SOFT_TISSUE

Explore this box plot interactively →