LTBP4

Across TCGA cell cohorts, LTBP4 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,009 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible LTBP4-associated GO terms across cancer lineages are Elastic fiber assembly, Calcium-independent cell-matrix adhesion, and Negative regulation of calcium ion export across plasma membrane. Each is linked with LTBP4 in more than 16 cancer types. Because this analysis shows association rather than direction, both LTBP4-to-partner and partner-to-LTBP4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Elastic fiber assembly grouped by LTBP4-low versus LTBP4-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LTBP4→partner) and Y-score (partner→LTBP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Elastic fiber assembly →	+1.072	+2.302	<.001	<.001	3	17
LUNG_SCLC	Calcium-independent cell-matrix adhesion →	+0.196	+2.336	<.001	.004	3	13
UPPER_AERODIGESTIVE_TRACT	Negative regulation of calcium ion export across plasma membrane →	+0.083	+2.342	<.001	<.001	3	11
LUNG_SCLC	IMP salvage →	+0.223	+1.990	<.001	<.001	3	11
URINARY_TRACT	Cellular response to morphine →	+0.136	+2.965	<.001	<.001	3	11
URINARY_TRACT	Cellular response to isoquinoline alkaloid →	+0.136	+2.965	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,009 associations by consensus.

Elastic fiber assembly by LTBP4 expression — URINARY_TRACT

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