LTBP2

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, LTBP2 protein abundance is significantly associated with the RNA expression of many other genes, with 15,643 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible LTBP2-associated genes across cancer lineages are C7, COMP, and SFRP4. Each is linked with LTBP2 in more than 9 cancer types. Because this analysis shows association rather than direction, both LTBP2-to-partner and partner-to-LTBP2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LTBP2 versus C7 in OV, with a Pearson correlation of 0.44.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LTBP2→partner) and Y-score (partner→LTBP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVC7 →+2.522+0.706<.001<.001310
COADCOMP →+2.191+0.907<.001<.00139
COADSFRP4 →+2.261+0.817<.001<.00139
UCECMGP →+1.570+0.766<.001<.00139
OVCCN2 →+1.742+0.869<.001<.00139
OVCOL10A1 →+2.181+0.630<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 15,643 associations by consensus.

LTBP2 vs C7 — OV

Per-sample scatter of LTBP2 vs C7 in OV (Pearson r = 0.44).

Explore this scatter interactively →

Exploration