LTBP2

Across TCGA cell cohorts, LTBP2 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,379 significant associations in total. BONE shows the largest number of these associations.

The most reproducible LTBP2-associated GO terms across cancer lineages are Positive regulation of cell junction assembly, Positive regulation of focal adhesion assembly, and Regulation of cell-substrate adhesion. Each is linked with LTBP2 in more than 15 cancer types. Because this analysis shows association rather than direction, both LTBP2-to-partner and partner-to-LTBP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of cell junction assembly grouped by LTBP2-low versus LTBP2-high in LUNG_NSCLC_LUAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LTBP2→partner) and Y-score (partner→LTBP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Positive regulation of cell junction assembly →	+0.089	+1.793	<.001	<.001	3	16
BONE	Positive regulation of focal adhesion assembly →	+0.207	+2.938	<.001	<.001	3	15
BONE	Regulation of cell-substrate adhesion →	+0.122	+2.609	<.001	<.001	3	15
LUNG_NSCLC_LUSC	Wound healing →	+0.123	+1.845	.001	.005	3	15
BONE	Fibrinolysis →	+1.748	+2.891	<.001	<.001	3	15
BONE	Dentinogenesis →	+2.108	+2.858	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,379 associations by consensus.

Positive regulation of cell junction assembly by LTBP2 expression — LUNG_NSCLC_LUAD

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