Across TCGA pan-cancer cohorts, LTB4R Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated LTB4R data layer compared with 26 for mass-spec protein and 4 for mass-spec protein.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher LTB4R Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated LTB4R expression acts as an unfavorable survival marker.

LUAD, ACC, and CHOL are the cancer types where LTB4R Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Median	All	0.083	0.788	<.001	25	view →
ACC	OS	Median	All	0.118	0.624	.038	6	view →
CHOL	OS	Median	All	0.155	0.725	.029	3	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: LTB4R tumor-vs-normal RNA expression · all LTB4R data types