LTB4R

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, LTB4R mutation is significantly associated with the total protein of many other genes, with 23 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LTB4R-associated genes across cancer lineages are Rictor_pT1135, EGFR_pY1068, and FOXO3a_pS318_S321. Each is linked with LTB4R in more than 1 cancer types. Because this analysis shows association rather than direction, both LTB4R-to-partner and partner-to-LTB4R results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LTB4R→partner) and Y-score (partner→LTB4R) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECRictor_pT1135 →-0.122-3.169.008.01932
UCECEGFR_pY1068 →-0.246-2.000.029.03231
UCECFOXO3a_pS318_S321 →-0.158-3.449.004.00531
UCECHeregulin →-0.126-2.000.023.03231
UCECJNK_pT183_Y185 →-0.243-3.794.001<.00131
UCECMEK1_p_S217_S221 →-0.245-2.000.046.03231
Each partner links to its Q-omics profile. Showing the 6 strongest of 23 associations by consensus.

Exploration