Across TCGA pan-cancer cohorts, LTB Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated LTB data layer compared with 24 for mass-spec protein.

The strongest signal is observed in small cell lung cancer (SCLC), where higher LTB Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated LTB expression acts as an unfavorable survival marker.

SCLC and BLCA are the cancer types where LTB Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SCLC	OS	Median	II,III,IV	0.082	0.702	<.001	30	view →
BLCA	DFS	Median	III,IV	0.107	0.575	<.001	12	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: LTB tumor-vs-normal RNA expression · all LTB data types