Across TCGA cell cohorts, LTB RNA expression is significantly associated with the go_rna of many other GO terms, with 3,406 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible LTB-associated GO terms across cancer lineages are Dendritic cell homeostasis, Canonical NF-kappaB signal transduction, and Regulation of type III interferon production. Each is linked with LTB in more than 8 cancer types. Because this analysis shows association rather than direction, both LTB-to-partner and partner-to-LTB results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LTB→partner) and Y-score (partner→LTB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Dendritic cell homeostasis →	-0.363	-1.349	<.001	<.001	3	9
LARGE_INTESTINE	Canonical NF-kappaB signal transduction →	+0.098	+0.845	<.001	.005	3	8
BREAST	Regulation of type III interferon production →	+0.973	+1.046	<.001	.001	3	8
BONE	Regulation of transcription initiation by RNA polymerase II →	+0.072	+0.240	.005	.002	2	9
CNS	Vertebrate eye-specific patterning →	+1.352	+0.263	<.001	<.001	3	8
OVARY	Regulation of tumor necrosis factor production →	+0.051	+1.528	.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,406 associations by consensus.

Exploration

LTB survival (RNA) · tumor vs normal (RNA) · all LTB data types