Across TCGA patient cohorts, LST1 protein abundance is significantly associated with the RNA expression of many other genes, with 7,757 significant associations in total. GBM shows the largest number of these associations.

The most reproducible LST1-associated genes across cancer lineages are PEBP1P3, MS4A14, and NABP1. Each is linked with LST1 in more than 3 cancer types. Because this analysis shows association rather than direction, both LST1-to-partner and partner-to-LST1 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LST1→partner) and Y-score (partner→LST1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PEBP1P3 →	+0.931	+0.590	<.001	<.001	3	4
COAD	MS4A14 →	+1.210	+1.086	.004	.009	3	3
GBM	NABP1 →	+1.077	+0.670	<.001	<.001	3	3
COAD	SPNS3 →	+0.936	+1.349	<.001	.005	3	3
GBM	SERPING1 →	+0.689	+0.388	.001	<.001	3	3
HNSC	SAMD3 →	+0.879	+0.927	.003	.009	2	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,757 associations by consensus.

Exploration

LST1 survival (RNA) · tumor vs normal (RNA) · all LST1 data types