Across TCGA cell cohorts, LST1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,607 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible LST1-associated GO terms across cancer lineages are Maintenance of protein localization in organelle, AMPA glutamate receptor clustering, and Glutamate receptor clustering. Each is linked with LST1 in more than 6 cancer types. Because this analysis shows association rather than direction, both LST1-to-partner and partner-to-LST1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LST1→partner) and Y-score (partner→LST1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Maintenance of protein localization in organelle →	+0.092	+0.169	<.001	.001	3	7
BLOOD_Lymphoma	AMPA glutamate receptor clustering →	+0.796	+1.604	<.001	<.001	3	6
BLOOD_Lymphoma	Glutamate receptor clustering →	+0.796	+1.604	<.001	<.001	3	6
STOMACH	Negative regulation of potassium ion transmembrane transporter activity →	-1.061	-0.181	.005	.007	3	6
STOMACH	Negative regulation of voltage-gated potassium channel activity →	-1.061	-0.181	.005	.007	3	6
LARGE_INTESTINE	Sensory perception of sound →	-0.078	-0.101	.003	.009	2	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,607 associations by consensus.

Exploration

LST1 survival (RNA) · tumor vs normal (RNA) · all LST1 data types