LSP1P2

Across TCGA pan-cancer cohorts, LSP1P2 RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of LSP1P2’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where LSP1P2 RNA is repressed in tumor relative to normal tissue. In most cancer types LSP1P2 is over-expressed in tumor, although a few such as COAD and KICH show the opposite, repressed pattern.

COAD, KICH, and BRCA are the cancer types where LSP1P2 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LSP1P2 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	Male	II,III,IV	−0.696	<.001	8	view →
KICH	Female	All	−0.664	<.001	8	view →
BRCA	Female	II,III,IV	−0.984	<.001	6	view →
HNSC	All	All	−0.779	<.001	6	view →
LUSC	Male	II,III,IV	−1.121	<.001	5	view →
UCEC	All	All	−0.710	.006	4	view →
THCA	All	All	−0.464	.003	3	view →
PAAD	Male	All	−1.500	.020	2	view →
PRAD	All	All	−0.345	.006	2	view →
READ	All	All	−0.669	.033	1	view →
LUAD	Male	II,III,IV	−0.652	.008	1	view →
STAD	Male	II,III,IV	−0.460	.049	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 12 lineages.

LSP1P2–COAD

Open the COAD breakdown →