LSMEM2

Across TCGA cell cohorts, LSMEM2 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,513 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible LSMEM2-associated GO terms across cancer lineages are Histone mRNA catabolic process, Telomere maintenance, and Mitochondrial gene expression. Each is linked with LSMEM2 in more than 5 cancer types. Because this analysis shows association rather than direction, both LSMEM2-to-partner and partner-to-LSMEM2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Histone mRNA catabolic process grouped by LSMEM2-low versus LSMEM2-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LSMEM2→partner) and Y-score (partner→LSMEM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Histone mRNA catabolic process →	+0.053	+0.081	.005	.003	3	6
KIDNEY	Telomere maintenance →	+0.041	+0.083	.006	.005	3	5
BLOOD_Lymphoma	Mitochondrial gene expression →	+0.060	+0.069	<.001	.008	3	5
BLOOD_Lymphoma	Positive regulation of transcription of nucleolar large rRNA by RNA polymerase I →	+0.096	+0.105	<.001	<.001	3	5
BLOOD_Lymphoma	Protein-RNA complex assembly →	+0.053	+0.068	<.001	.007	3	5
BLOOD_Lymphoma	Ribosome biogenesis →	+0.060	+0.068	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,513 associations by consensus.

Histone mRNA catabolic process by LSMEM2 expression — LUNG_SCLC

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