LSM7

Across TCGA pan-cancer cohorts, LSM7 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated LSM7 data layer compared with 29 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher LSM7 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated LSM7 expression acts as an unfavorable survival marker, although some lineages such as LSCC and GBM show a favorable association.

LSCC, GBM, and HNSC are the cancer types where LSM7 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	DFS	Median	II,III,IV	0.814	0.565	.018	9	view →
GBM	DFS	Quartile	All	0.478	0.194	.003	7	view →
HNSC	OS	Median	All	0.772	0.931	.006	5	view →
CCRCC	DFS	Median	III,IV	0.774	0.207	.047	2	view →
LUAD	OS	Median	III,IV	0.607	0.241	.037	2	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

LSM7–LSCC (DFS)

Open the LSCC breakdown →