LSM7

Across TCGA cell cohorts, LSM7 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,381 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible LSM7-associated GO terms across cancer lineages are Cellular response to topologically incorrect protein, Cellular response to unfolded protein, and Response to unfolded protein. Each is linked with LSM7 in more than 16 cancer types. Because this analysis shows association rather than direction, both LSM7-to-partner and partner-to-LSM7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cellular response to topologically incorrect protein grouped by LSM7-low versus LSM7-high in CNS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LSM7→partner) and Y-score (partner→LSM7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	Cellular response to topologically incorrect protein →	-0.067	-0.444	<.001	.007	3	17
BLOOD_Myeloma	Cellular response to unfolded protein →	-0.092	-0.609	<.001	.003	2	16
LARGE_INTESTINE	Response to unfolded protein →	-0.070	-0.387	.001	.006	3	15
BLOOD_Myeloma	Endoplasmic reticulum unfolded protein response →	-0.088	-0.620	.001	.007	2	15
BONE	Negative regulation of neuron apoptotic process →	-0.115	-0.656	.002	<.001	3	13
OVARY	Response to topologically incorrect protein →	-0.081	-0.557	<.001	.004	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,381 associations by consensus.

Cellular response to topologically incorrect protein by LSM7 expression — CNS

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