LSM5

Across TCGA patient cohorts, LSM5 protein abundance is significantly associated with the RNA expression of many other genes, with 21,026 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible LSM5-associated genes across cancer lineages are SLC31A2, RASGRP4, and CSF3R. Each is linked with LSM5 in more than 3 cancer types. Because this analysis shows association rather than direction, both LSM5-to-partner and partner-to-LSM5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LSM5 versus SLC31A2 in GBM, with a Pearson correlation of -0.37.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LSM5→partner) and Y-score (partner→LSM5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SLC31A2 →	-0.586	-0.345	<.001	<.001	3	4
GBM	RASGRP4 →	-0.426	-0.275	<.001	.002	3	4
GBM	CSF3R →	-0.992	-0.460	<.001	<.001	3	4
HNSC	CXCR1 →	-0.976	-0.204	.002	.003	3	4
PDAC	CXCR2 →	-0.925	-0.412	<.001	<.001	3	4
CCRCC	ATP6V0E1 →	-0.408	-0.158	<.001	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 21,026 associations by consensus.

LSM5 vs SLC31A2 — GBM

Explore this scatter interactively →