LSM5

Across TCGA cell cohorts, LSM5 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,767 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible LSM5-associated GO terms across cancer lineages are Establishment of meiotic spindle orientation, Protein localization to kinetochore, and Regulation of protein localization to endoplasmic reticulum. Each is linked with LSM5 in more than 14 cancer types. Because this analysis shows association rather than direction, both LSM5-to-partner and partner-to-LSM5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Establishment of meiotic spindle orientation grouped by LSM5-low versus LSM5-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LSM5→partner) and Y-score (partner→LSM5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Establishment of meiotic spindle orientation →	+0.127	+0.795	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Protein localization to kinetochore →	+0.120	+1.133	.002	<.001	3	14
KIDNEY	Regulation of protein localization to endoplasmic reticulum →	-0.129	-0.883	.002	.002	3	14
UPPER_AERODIGESTIVE_TRACT	Regulation of ATP metabolic process →	-0.073	-1.402	.002	<.001	3	14
BLOOD_Leukemia	Positive regulation of cell morphogenesis →	-0.065	-0.822	<.001	<.001	3	13
SKIN	Meiotic cell cycle →	+0.051	+0.696	.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,767 associations by consensus.

Establishment of meiotic spindle orientation by LSM5 expression — BLOOD_Lymphoma

Explore this box plot interactively →