LSM3P4

Across TCGA patient cohorts, LSM3P4 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,049 significant associations in total. STAD shows the largest number of these associations.

The most reproducible LSM3P4-associated GO terms across cancer lineages are Alternative mRNA splicing, via spliceosome, Regulation of nucleocytoplasmic transport, and Negative regulation of RNA catabolic process. Each is linked with LSM3P4 in more than 8 cancer types. Because this analysis shows association rather than direction, both LSM3P4-to-partner and partner-to-LSM3P4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Alternative mRNA splicing, via spliceosome grouped by LSM3P4-low versus LSM3P4-high in LUAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LSM3P4→partner) and Y-score (partner→LSM3P4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	Alternative mRNA splicing, via spliceosome →	+0.051	+0.085	<.001	.005	3	9
STAD	Regulation of nucleocytoplasmic transport →	+0.039	+0.125	<.001	<.001	3	9
STAD	Negative regulation of RNA catabolic process →	+0.037	+0.090	<.001	<.001	3	9
KIRC	Regulation of RNA splicing →	+0.044	+0.048	<.001	.002	3	9
STAD	Actin polymerization or depolymerization →	+0.051	+0.188	<.001	<.001	3	8
STAD	Phospholipid biosynthetic process →	+0.037	+0.125	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,049 associations by consensus.

Alternative mRNA splicing, via spliceosome by LSM3P4 expression — LUAD

Explore this box plot interactively →