Across TCGA cell cohorts, LSM2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,728 significant associations in total. BONE shows the largest number of these associations.

The most reproducible LSM2-associated GO terms across cancer lineages are Protein peptidyl-prolyl isomerization, DNA replication initiation, and DNA replication checkpoint signaling. Each is linked with LSM2 in more than 17 cancer types. Because this analysis shows association rather than direction, both LSM2-to-partner and partner-to-LSM2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LSM2→partner) and Y-score (partner→LSM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Protein peptidyl-prolyl isomerization →	+0.126	+0.766	.004	.004	2	18
BLOOD_Myeloma	DNA replication initiation →	+0.212	+0.963	<.001	<.001	3	16
BLOOD_Myeloma	DNA replication checkpoint signaling →	+0.165	+0.825	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Double-strand break repair via break-induced replication →	+0.249	+1.161	<.001	<.001	3	13
BREAST	Meiotic chromosome segregation →	+0.119	+0.728	.001	.003	3	13
PANCREAS	Positive regulation of DNA replication →	+0.072	+0.721	.005	.002	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,728 associations by consensus.

Exploration

LSM2 survival (RNA) · tumor vs normal (RNA) · all LSM2 data types