LSM14B

Across TCGA cell cohorts, LSM14B RNA expression is significantly associated with the go_rna of many other GO terms, with 5,261 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible LSM14B-associated GO terms across cancer lineages are Maternal-to-zygotic transition of gene expression, Regulation of double-strand break repair via homologous recombination, and Regulation of transcription initiation by RNA polymerase II. Each is linked with LSM14B in more than 17 cancer types. Because this analysis shows association rather than direction, both LSM14B-to-partner and partner-to-LSM14B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Maternal-to-zygotic transition of gene expression grouped by LSM14B-low versus LSM14B-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LSM14B→partner) and Y-score (partner→LSM14B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Maternal-to-zygotic transition of gene expression →	+0.311	+0.965	.003	.002	3	18
OVARY	Regulation of double-strand break repair via homologous recombination →	+0.087	+0.807	<.001	<.001	3	16
STOMACH	Regulation of transcription initiation by RNA polymerase II →	+0.065	+0.976	<.001	<.001	3	16
UPPER_AERODIGESTIVE_TRACT	Transcription initiation at RNA polymerase II promoter →	+0.061	+0.750	<.001	<.001	3	16
URINARY_TRACT	Regulation of DNA-templated transcription initiation →	+0.072	+0.838	<.001	<.001	3	15
LUNG_SCLC	Regulation of stem cell population maintenance →	+0.077	+0.637	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,261 associations by consensus.

Maternal-to-zygotic transition of gene expression by LSM14B expression — OESOPHAGUS

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