LSM14B

Across TCGA cell cohorts, LSM14B mutation is significantly associated with the RNA expression of many other genes, with 12 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible LSM14B-associated genes across cancer lineages are RIPPLY1, PGK2, and A3GALT2. Each is linked with LSM14B in more than 1 cancer types. Because this analysis shows association rather than direction, both LSM14B-to-partner and partner-to-LSM14B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RIPPLY1 grouped by LSM14B-low versus LSM14B-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LSM14B→partner) and Y-score (partner→LSM14B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	RIPPLY1 →	+0.030	+4.191	.001	.007	3	1
BLOOD_Lymphoma	PGK2 →	+0.045	+4.523	<.001	.004	3	1
BLOOD_Lymphoma	A3GALT2 →	+0.030	+4.191	<.001	.007	3	1
BLOOD_Lymphoma	FSCB →	+0.042	+4.350	<.001	.005	3	1
LARGE_INTESTINE	C6orf118 →	+0.108	+3.793	.004	.007	3	1
LARGE_INTESTINE	OR2D3 →	+0.027	+4.510	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

RIPPLY1 by LSM14B expression — BLOOD_Lymphoma

Explore this box plot interactively →