LSM11

Across TCGA cell cohorts, LSM11 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,878 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible LSM11-associated GO terms across cancer lineages are Centrosome cycle, Heterochromatin formation, and Establishment of mitotic spindle localization. Each is linked with LSM11 in more than 14 cancer types. Because this analysis shows association rather than direction, both LSM11-to-partner and partner-to-LSM11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Centrosome cycle grouped by LSM11-low versus LSM11-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LSM11→partner) and Y-score (partner→LSM11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Centrosome cycle →	+0.093	+0.586	<.001	<.001	3	15
STOMACH	Heterochromatin formation →	+0.065	+0.729	<.001	<.001	3	14
SOFT_TISSUE	Establishment of mitotic spindle localization →	+0.144	+0.656	<.001	<.001	3	14
BONE	Metaphase/anaphase transition of cell cycle →	+0.198	+0.873	.005	.003	3	14
SOFT_TISSUE	Regulation of sister chromatid cohesion →	+0.152	+0.759	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Heterochromatin organization →	+0.061	+0.649	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,878 associations by consensus.

Centrosome cycle by LSM11 expression — PANCREAS

Explore this box plot interactively →