LSG1

Across TCGA patient cohorts, LSG1 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,042 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible LSG1-associated proteins across cancer lineages are GMPS, UBXN7, and FXR1. Each is linked with LSG1 in more than 7 cancer types. Because this analysis shows association rather than direction, both LSG1-to-partner and partner-to-LSG1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LSG1 versus GMPS in LSCC, with a Pearson correlation of 0.65.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LSG1→partner) and Y-score (partner→LSG1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	GMPS →	+0.598	+0.970	<.001	<.001	3	8
LSCC	UBXN7 →	+0.718	+1.096	<.001	<.001	3	8
LSCC	FXR1 →	+0.549	+1.020	<.001	<.001	3	8
LSCC	ABCF3 →	+0.411	+0.891	<.001	<.001	3	7
LSCC	PCYT1A →	+0.621	+0.790	<.001	<.001	3	7
LSCC	ECT2 →	+0.691	+1.009	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,042 associations by consensus.

LSG1 vs GMPS — LSCC

Explore this scatter interactively →