LSG1

Across TCGA patient cohorts, LSG1 mutation is significantly associated with the RNA expression of many other genes, with 3,062 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LSG1-associated genes across cancer lineages are LINC01760, MIR7845, and ATP6V1D. Each is linked with LSG1 in more than 2 cancer types. Because this analysis shows association rather than direction, both LSG1-to-partner and partner-to-LSG1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC01760 grouped by LSG1-low versus LSG1-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LSG1→partner) and Y-score (partner→LSG1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	LINC01760 →	+0.104	+4.444	<.001	.006	3	3
LIHC	MIR7845 →	+0.414	+5.268	<.001	.006	3	2
SKCM	ATP6V1D →	+0.516	+2.745	.001	.003	3	2
SKCM	BCCIP →	+0.536	+3.507	.007	.002	3	2
UCEC	PSMD9 →	+0.395	+2.823	<.001	.001	3	2
SKCM	CORO1C →	+0.579	+2.732	.002	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,062 associations by consensus.

LINC01760 by LSG1 expression — LUAD

Explore this box plot interactively →