LSG1

Across TCGA cell cohorts, LSG1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,834 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible LSG1-associated GO terms across cancer lineages are Negative regulation of cell cycle process, Ribosome localization, and Ribosomal subunit export from nucleus. Each is linked with LSG1 in more than 16 cancer types. Because this analysis shows association rather than direction, both LSG1-to-partner and partner-to-LSG1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of cell cycle process grouped by LSG1-low versus LSG1-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LSG1→partner) and Y-score (partner→LSG1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Negative regulation of cell cycle process →	+0.086	+1.276	<.001	<.001	3	17
UPPER_AERODIGESTIVE_TRACT	Ribosome localization →	+0.118	+1.120	<.001	.001	3	17
UPPER_AERODIGESTIVE_TRACT	Ribosomal subunit export from nucleus →	+0.118	+1.120	<.001	.001	3	17
URINARY_TRACT	Maintenance of centrosome location →	+0.150	+0.857	<.001	<.001	3	16
UPPER_AERODIGESTIVE_TRACT	Double-strand break repair via nonhomologous end joining →	+0.066	+0.889	<.001	.003	3	16
BONE	Double-strand break repair via homologous recombination →	+0.094	+0.906	.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,834 associations by consensus.

Negative regulation of cell cycle process by LSG1 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →