LRWD1

Across TCGA cell cohorts, LRWD1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,039 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible LRWD1-associated GO terms across cancer lineages are Pre-mRNA catabolic process, DNA-templated transcription termination, and Nuclear export. Each is linked with LRWD1 in more than 16 cancer types. Because this analysis shows association rather than direction, both LRWD1-to-partner and partner-to-LRWD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Pre-mRNA catabolic process grouped by LRWD1-low versus LRWD1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LRWD1→partner) and Y-score (partner→LRWD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Pre-mRNA catabolic process →	+0.246	+1.024	.001	.005	3	17
UPPER_AERODIGESTIVE_TRACT	DNA-templated transcription termination →	+0.094	+0.985	.001	<.001	3	14
BONE	Nuclear export →	+0.111	+1.148	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	DNA replication initiation →	+0.156	+1.074	<.001	<.001	3	13
LARGE_INTESTINE	Transcription initiation at RNA polymerase III promoter →	+0.089	+0.868	<.001	<.001	3	13
BONE	Mitochondrial DNA metabolic process →	+0.095	+0.764	.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,039 associations by consensus.

Pre-mRNA catabolic process by LRWD1 expression — BONE

Explore this box plot interactively →