LRTM2

Across TCGA patient cohorts, LRTM2 protein abundance is significantly associated with the RNA expression of many other genes, with 436 significant associations in total. GBM shows the largest number of these associations.

The most reproducible LRTM2-associated genes across cancer lineages are SYNGR1, CACNA1I, and CHGA. Each is linked with LRTM2 in more than 1 cancer types. Because this analysis shows association rather than direction, both LRTM2-to-partner and partner-to-LRTM2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LRTM2 versus SYNGR1 in GBM, with a Pearson correlation of 0.55.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LRTM2→partner) and Y-score (partner→LRTM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SYNGR1 →	+0.762	+0.515	.007	.001	3	1
GBM	CACNA1I →	+0.910	+0.611	<.001	.002	3	1
GBM	CHGA →	+2.116	+0.605	<.001	.001	3	1
GBM	HRH3 →	+0.849	+0.633	.002	.004	3	1
GBM	SLC32A1 →	+1.639	+0.638	<.001	.002	3	1
GBM	CELF4 →	+1.014	+0.488	.007	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 436 associations by consensus.

LRTM2 vs SYNGR1 — GBM

Explore this scatter interactively →