LRTM2

Across TCGA cell cohorts, LRTM2 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,291 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible LRTM2-associated GO terms across cancer lineages are Regulation of actin filament-based movement, Axoneme assembly, and Alpha-beta T cell activation. Each is linked with LRTM2 in more than 5 cancer types. Because this analysis shows association rather than direction, both LRTM2-to-partner and partner-to-LRTM2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of actin filament-based movement grouped by LRTM2-low versus LRTM2-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LRTM2→partner) and Y-score (partner→LRTM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Regulation of actin filament-based movement →	-0.098	-1.147	.004	.008	3	6
LARGE_INTESTINE	Axoneme assembly →	-0.039	-0.049	<.001	<.001	2	6
BREAST	Alpha-beta T cell activation →	-0.121	-0.598	<.001	<.001	3	5
LARGE_INTESTINE	Positive regulation of post-translational protein modification →	+0.040	+0.048	<.001	.001	3	4
LARGE_INTESTINE	Positive regulation of axon guidance →	+0.789	+0.040	.004	.002	3	4
LARGE_INTESTINE	Regulation of telomere maintenance in response to DNA damage →	+0.056	+0.059	.003	.007	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,291 associations by consensus.

Regulation of actin filament-based movement by LRTM2 expression — LUNG_SCLC

Explore this box plot interactively →