LRTM1

Across TCGA patient cohorts, LRTM1 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,756 significant associations in total. GBM shows the largest number of these associations.

The most reproducible LRTM1-associated proteins across cancer lineages are CACNA2D1, DDAH1, and PRKAR2B. Each is linked with LRTM1 in more than 3 cancer types. Because this analysis shows association rather than direction, both LRTM1-to-partner and partner-to-LRTM1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LRTM1 versus CACNA2D1 in LSCC, with a Pearson correlation of 0.38.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LRTM1→partner) and Y-score (partner→LRTM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	CACNA2D1 →	+0.705	+0.926	<.001	<.001	3	4
HNSC	DDAH1 →	+0.367	+0.683	.001	<.001	3	4
HNSC	PRKAR2B →	+0.506	+0.778	<.001	<.001	3	4
GBM	FNDC3B →	-0.446	-0.608	<.001	.001	3	4
UCEC	OSBPL6_S290 →	+1.462	+1.090	.001	.003	3	4
GBM	MRC2 →	-0.583	-0.660	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,756 associations by consensus.

LRTM1 vs CACNA2D1 — LSCC

Explore this scatter interactively →