LRSAM1

Across TCGA patient cohorts, LRSAM1 protein abundance is significantly associated with the RNA expression of many other genes, with 8,077 significant associations in total. GBM shows the largest number of these associations.

The most reproducible LRSAM1-associated genes across cancer lineages are PTPA, PPP6C, and TRUB2. Each is linked with LRSAM1 in more than 5 cancer types. Because this analysis shows association rather than direction, both LRSAM1-to-partner and partner-to-LRSAM1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LRSAM1 versus PTPA in BRCA, with a Pearson correlation of 0.44.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LRSAM1→partner) and Y-score (partner→LRSAM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	PTPA →	+0.543	+0.218	<.001	<.001	3	6
OV	PPP6C →	+0.605	+0.278	<.001	.001	3	6
OV	TRUB2 →	+0.589	+0.308	<.001	<.001	3	6
OV	URM1 →	+0.642	+0.292	<.001	.001	3	6
HNSC	CDK9 →	+0.481	+0.303	<.001	<.001	3	5
BRCA	SH3GLB2 →	+1.010	+0.329	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,077 associations by consensus.

LRSAM1 vs PTPA — BRCA

Explore this scatter interactively →