LRSAM1

Across TCGA patient cohorts, LRSAM1 mutation is significantly associated with the RNA expression of many other genes, with 2,489 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LRSAM1-associated genes across cancer lineages are GOLGA6L11P, OR52U1P, and RN7SL255P. Each is linked with LRSAM1 in more than 2 cancer types. Because this analysis shows association rather than direction, both LRSAM1-to-partner and partner-to-LRSAM1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GOLGA6L11P grouped by LRSAM1-low versus LRSAM1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LRSAM1→partner) and Y-score (partner→LRSAM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	GOLGA6L11P →	+0.009	+2.761	<.001	.009	3	3
HNSC	OR52U1P →	+0.040	+3.556	<.001	.007	3	2
CESC	RN7SL255P →	+0.123	+4.337	<.001	<.001	3	2
CESC	MIR6133 →	+0.108	+4.020	<.001	.009	3	2
HNSC	IGLL4P →	+1.084	+3.709	<.001	.007	3	2
UCEC	SNX3P1Y →	+0.060	+3.723	<.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,489 associations by consensus.

GOLGA6L11P by LRSAM1 expression — UCEC

Explore this box plot interactively →