LRSAM1

Across TCGA cell cohorts, LRSAM1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,635 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible LRSAM1-associated GO terms across cancer lineages are Positive regulation of xenophagy, Positive regulation of autophagosome assembly, and Positive regulation of vacuole organization. Each is linked with LRSAM1 in more than 17 cancer types. Because this analysis shows association rather than direction, both LRSAM1-to-partner and partner-to-LRSAM1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of xenophagy grouped by LRSAM1-low versus LRSAM1-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LRSAM1→partner) and Y-score (partner→LRSAM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	Positive regulation of xenophagy →	+0.170	+0.851	<.001	<.001	3	18
STOMACH	Positive regulation of autophagosome assembly →	+0.143	+0.940	<.001	<.001	3	15
BREAST	Positive regulation of vacuole organization →	+0.093	+0.866	<.001	<.001	3	13
BONE	Transcription pausing by RNA polymerase II →	+0.164	+0.618	<.001	<.001	3	13
STOMACH	Positive regulation of autophagy →	+0.075	+1.015	<.001	<.001	3	12
OESOPHAGUS	Cilium or flagellum-dependent cell motility →	-0.133	-1.205	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,635 associations by consensus.

Positive regulation of xenophagy by LRSAM1 expression — BLOOD_Myeloma

Explore this box plot interactively →