LRRTM4-AS1

Across TCGA pan-cancer cohorts, LRRTM4-AS1 RNA is linked to patient survival in 15 of 34 cancer types, making it the most broadly survival-associated LRRTM4-AS1 data layer.

The strongest signal is observed in mesothelioma (MESO), where higher LRRTM4-AS1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated LRRTM4-AS1 expression acts as an unfavorable survival marker, although some lineages such as LGG and PAAD show a favorable association.

MESO, CESC, and KIRP are the cancer types where LRRTM4-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	OS	Tertile	III,IV	0.098	0.579	.001	72	view →
CESC	OS	Tertile	II,III,IV	0.193	0.764	.004	72	view →
KIRP	OS	Tertile	II,III,IV	0.161	0.771	.002	45	view →
LUSC	OS	Tertile	III,IV	0.335	0.704	.003	36	view →
SARC	OS	Tertile	All	0.252	0.771	<.001	27	view →
LIHC	OS	Tertile	III,IV	0.321	0.747	.026	27	view →
PRAD	DFS	Tertile	All	0.762	0.937	.003	24	view →
DLBC	DFS	Tertile	III,IV	0.070	0.855	.008	18	view →
STAD	DFS	Tertile	All	0.561	0.735	.040	18	view →
LUAD	DFS	Tertile	IV	0.342	0.893	<.001	18	view →
LGG	DFS	Median	All	0.468	0.343	.005	15	view →
PAAD	DFS	Tertile	All	1.000	0.271	.036	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 15 lineages.

LRRTM4-AS1–MESO (OS)

Open the MESO breakdown →