Across TCGA patient cohorts, LRRTM3 protein abundance is significantly associated with the RNA expression of many other genes, with 1,287 significant associations in total. GBM shows the largest number of these associations.

The most reproducible LRRTM3-associated genes across cancer lineages are SEZ6L, PATZ1, and DDX17. Each is linked with LRRTM3 in more than 1 cancer types. Because this analysis shows association rather than direction, both LRRTM3-to-partner and partner-to-LRRTM3 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LRRTM3→partner) and Y-score (partner→LRRTM3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SEZ6L →	+1.491	+0.369	<.001	<.001	3	1
GBM	PATZ1 →	+0.431	+0.354	.001	.004	3	1
GBM	DDX17 →	+0.304	+0.331	.003	.005	3	1
GBM	PPP6R2 →	+0.328	+0.380	<.001	.002	3	1
GBM	RBFOX2 →	+0.480	+0.338	<.001	.005	3	1
GBM	SAMM50 →	+0.224	+0.400	.008	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,287 associations by consensus.

Exploration

LRRTM3 survival (RNA) · tumor vs normal (RNA) · all LRRTM3 data types