Across TCGA patient cohorts, LRRTM3 mutation is significantly associated with the RNA expression of many other genes, with 3,910 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LRRTM3-associated genes across cancer lineages are CIDECP1, APTX, and DCP1A. Each is linked with LRRTM3 in more than 3 cancer types. Because this analysis shows association rather than direction, both LRRTM3-to-partner and partner-to-LRRTM3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LRRTM3→partner) and Y-score (partner→LRRTM3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CIDECP1 →	+0.380	+1.741	<.001	<.001	3	4
UCEC	APTX →	+0.269	+2.269	.001	<.001	3	4
UCEC	DCP1A →	+0.356	+2.364	.006	.002	3	3
UCEC	ZNF367 →	+0.595	+1.688	<.001	.001	3	3
SKCM	NOLC1 →	+0.479	+1.879	.003	.004	3	3
LUAD	C11orf80 →	+0.518	+2.608	.002	.006	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,910 associations by consensus.

Exploration

LRRTM3 survival (RNA) · tumor vs normal (RNA) · all LRRTM3 data types