LRRN3

Across TCGA patient cohorts, LRRN3 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,439 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible LRRN3-associated proteins across cancer lineages are CAVIN1, EHD2, and ISG20. Each is linked with LRRN3 in more than 5 cancer types. Because this analysis shows association rather than direction, both LRRN3-to-partner and partner-to-LRRN3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LRRN3 versus CAVIN1 in BRCA, with a Pearson correlation of 0.51.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LRRN3→partner) and Y-score (partner→LRRN3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	CAVIN1 →	+0.774	+0.724	<.001	<.001	3	6
BRCA	EHD2 →	+0.837	+0.746	<.001	<.001	3	6
CCRCC	ISG20 →	-0.602	-0.555	<.001	<.001	3	6
BRCA	KANK2 →	+0.621	+0.771	<.001	<.001	3	5
BRCA	RPL7 →	-0.227	-0.614	<.001	<.001	3	5
GBM	GTF2I →	+0.328	+0.614	.002	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,439 associations by consensus.

LRRN3 vs CAVIN1 — BRCA

Explore this scatter interactively →