LRRN3

Across TCGA patient cohorts, LRRN3 protein abundance is significantly associated with the RNA expression of many other genes, with 138 significant associations in total. GBM shows the largest number of these associations.

The most reproducible LRRN3-associated genes across cancer lineages are MTR, EGR1, and SLCO1C1. Each is linked with LRRN3 in more than 1 cancer types. Because this analysis shows association rather than direction, both LRRN3-to-partner and partner-to-LRRN3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LRRN3 versus MTR in GBM, with a Pearson correlation of 0.87.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LRRN3→partner) and Y-score (partner→LRRN3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	MTR →	+0.543	+0.626	<.001	.001	3	1
GBM	EGR1 →	-2.086	-0.626	.005	.001	3	1
GBM	SLCO1C1 →	-2.186	-0.620	.007	.001	3	1
GBM	NIPA2 →	-0.486	-0.626	<.001	.001	3	1
GBM	RGPD5 →	+0.061	+0.511	.004	<.001	3	1
GBM	PWWP3B →	+1.011	+0.511	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 138 associations by consensus.

LRRN3 vs MTR — GBM

Explore this scatter interactively →