LRRN3

Across TCGA cell cohorts, LRRN3 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,763 significant associations in total. CNS shows the largest number of these associations.

The most reproducible LRRN3-associated GO terms across cancer lineages are Golgi vesicle transport, Post-Golgi vesicle-mediated transport, and Regulation of microtubule-based process. Each is linked with LRRN3 in more than 6 cancer types. Because this analysis shows association rather than direction, both LRRN3-to-partner and partner-to-LRRN3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Golgi vesicle transport grouped by LRRN3-low versus LRRN3-high in CNS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LRRN3→partner) and Y-score (partner→LRRN3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	Golgi vesicle transport →	+0.053	+1.362	<.001	<.001	3	7
UPPER_AERODIGESTIVE_TRACT	Post-Golgi vesicle-mediated transport →	+0.050	+0.068	<.001	.003	3	6
LUNG_SCLC	Regulation of microtubule-based process →	+0.057	+1.544	.002	.001	3	6
UPPER_AERODIGESTIVE_TRACT	Protein polyubiquitination →	+0.046	+0.092	<.001	.006	3	5
UPPER_AERODIGESTIVE_TRACT	Negative regulation of calcium ion export across plasma membrane →	+0.058	+0.061	<.001	.009	3	5
CNS	Cell division →	+0.050	+1.279	<.001	<.001	2	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,763 associations by consensus.

Golgi vesicle transport by LRRN3 expression — CNS

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